Syndromic Testing

Syndromic Testing for Infectious Diseases: Respiratory Infections

Overview

Upper respiratory infections are one of the leading causes of morbidity and mortality worldwide, and may result in a range of symptoms, from mild clinical manifestations, such as a cough, pharyngitis, or runny nose to life-threatening disease that may involve respiratory distress. Infections of the upper respiratory tract are extremely common with an estimated 17.2 billion cases worldwide in 2015. As you’re probably well aware from personal experience, individuals can have multiple upper respiratory infections each year, with children less than 5 years old experiencing a mean of 6.1 episodes per year, and adults older than 40 suffering from about 4 upper respiratory infections each year.

We now have an appreciation that these infections can be caused by a variety of pathogens. Viruses account for the majority of upper respiratory infections, and they frequently involve coronaviruses and rhinoviruses, which are causes of the common cold. In addition, influenza is an important cause of respiratory infections and demonstrates a pronounced seasonality with the vast majority of cases occurring between the months of November and March each year in the United States. Bacteria can also cause upper respiratory tract infections with Streptococcus pyogenes being the etiologic agent for strep throat and Bordetella pertussis causing pertussis ( or whooping cough). Other bacteria, such as Mycoplasma pneumoniae can also be associated with upper respiratory illness.

Biofire Testing

BioFire is the new standard for syndromic infectious disease diagnostics. Simple, fast and comprehensive, the FilmArray delivers accurate results in about an hour. The right test, the first time can impact all areas of patient care. Healthcare providers can see faster diagnoses and improved antibiotic stewardship. Biofire tests 24 pathogens and 3 antibiotic resistance genes associated with bloodstream infections. With just one test you can identify pathogens in 9 out of 10 positive blood cultures in about an hour with only 2 minutes of hands-on time. Two-Three weeks of testings can be done within an hour, this means that early diagnosis and curb of the diseases.

Viruses that Biofire Diagnoses

Bacteria that Biofire Diagnoses

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